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Financement de l’UE (4 023 427 €) : Transcender les limites de la recherche translationnelle sur la sclérose en plaques et les troubles du spectre autistique - Spectral, trouble cérébral, résultats … Hor08/07/2025 Programme de recherche et d'innovation de l'UE « Horizon »
Texte
Transcender les limites de la recherche translationnelle sur la sclérose en plaques et les troubles du spectre autistique - Spectral, trouble cérébral, résultats pour les patients, cognition, effet, symptômes
TRANSCEND brings together expertise in biomedical, computational, behavioural, clinical, epidemiological and philosophical research to advance translational research in medicine. TRANSCEND aims to add to the chronological and epistemic order of research from bench to bedside to practice with a more networked-based understanding of translation. This is particularly important in translational research on complex and chronic neurological conditions where the few low-hanging fruits of reductionist approaches seem to have been picked. TRANSCEND involves nine interlinked laboratories from clinical, biomedical, metamethodological, and philosophical sub-projects, which focus on autism spectrum disorder and multiple sclerosis. These conditions are characterised by an interconnected set of physical, cognitive and psychological symptoms, and unknown underlying disease mechanisms. While healthcare has been moving away from a purely single-cause view of medicine towards interconnected concepts of positive health, such a more complicated and nuanced notion of health and dis/ability is unintegrated within biomedical research. Most research designs are not well-suited to consider patient-relevant outcomes, the biological and social complexity of these conditions, and their implications in real-world healthcare settings, because their epistemology is oriented towards purification and reduction concerning research questions, disease models, and experiments. TRANSCEND proposes an integrative approach to translational research that embraces instead of reduces the complexity and diversity of the biological, clinical and social manifestations of the diagnoses. It will provide an innovative, interdisciplinary training along four research objectives to overcome key limitations of translational research on complex, chronic conditions: (1) making animal models more translational; (2) focusing on patient outcomes and scoping “disease” categories; (3) rethinking theragnostic strategies.
| BUNDESMINISTERIUM FUER GESUNDHEIT | ? |
| Aarhus Universitet | 671 780 € |
| Katholieke Universiteit Leuven | 288 540 € |
| Kobenhavns Universitet | 335 890 € |
| STICHTING AMSTERDAM UMC | 305 286 € |
| STICHTING RADBOUD UNIVERSITEIT | 610 572 € |
| Universidade do Porto | 279 445 € |
| UNIVERSITAET BIELEFELD | 290 272 € |
| UNIVERSITAIR MEDISCH CENTRUM UTRECHT | 305 286 € |
| Universita Vita-Salute SAN Raffaele | 281 755 € |
| Universite Bordeaux Montaigne | 314 669 € |
| Universitetet I Oslo | 339 932 € |
https://cordis.europa.eu/project/id/101226660
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : BUNDESMINISTERIUM FUER GESUNDHEIT, Bonn, Allemagne.
