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Financement de l’UE (7 787 818 €) : Exploitation durable de composés biosourcés révélés et conçus à partir de sources naturelles. Hor21/05/2021 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Exploitation durable de composés biosourcés révélés et conçus à partir de sources naturelles.
SECRETed is an EU-H2020 multidisciplinary project involving multiple stakeholders and with a strong participation of SMEs to fully exploit the potential of aquatic biotechnology and produce novel industrial products for the agrochemical, pharmaceutical, cosmetic and chemistry sectors. SECRETed will develop novel hybrid molecules with tailor-made properties obtained from the combination of biosynthetic genes of amphiphilic compounds (biosurfactants and siderophores) produced by marine and extremophilic microorganisms. The project will focus on reutilizing previous sampling efforts by screening already collected microbial collections from previous European initiatives. Machine Learning algorithms (ML) will be deployed to reveal the genetic mechanisms responsible for their biosynthesis and to expand the chemical diversity of such bio-based compounds. To this end, databases inspection and new collected data will be employed to construct a unique microbial amphiphilic compound chemical space comprehending molecular structures, physicochemical characteristics, associated bioactivities and revealed genetic mechanisms responsible for their biosynthesis. To expand the chemical diversity and enhance the industrial sustainable exploitation of such bio-based compounds, Biosynthetic gene clusters (BGCs) in charge of the production of these molecules will be reverse engineered by standardizing and modularizing the genetic elements comprising such clusters. Their potential benefits will be broadened by looking for Industry-driven (agrochemical, cosmetic, nutrition and health) formulations based on the engineered combinations of the genetic elements expressed in suitable microbial hosts. New strains will then be designed, built and tested in an iterative process for the development of viable and sustainable industrial processes.
| Accuplex Diagnostics Ltd. | 321 875 € |
| Bio Base Europe Pilot Plant VZW | 758 125 € |
| Blue Synergy SL | 313 500 € |
| Eberhard Karls Universitaet Tuebingen | 498 250 € |
| Ethniko Kai Kapodistriako Panepistimio Athinon | 546 500 € |
| Exelisis ΙΚΕ | 377 000 € |
| Idener Research & Development AIE | 933 750 € |
| Imperial College of Science Technology and Medicine | 472 320 € |
| Lunds Universitet | 541 250 € |
| Matis OHF | 605 063 € |
| Pharma Mar SA | 334 730 € |
| Sphera Encapsulation Srl | 480 454 € |
| Stazione Zoologica Anton Dohrn | 408 375 € |
| Sylentis SA | 579 112 € |
| Universidad de Sevilla | 617 515 € |
https://cordis.europa.eu/project/id/101000794
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.
