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Financement de l’UE (6 998 852 €) : Vers l’amélioration de l’élevage des ruminants par des approches génomiques et épigénomiques Hor21/05/2021 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Vers l’amélioration de l’élevage des ruminants par des approches génomiques et épigénomiques
More sustainable breeding programs and linked technologies need to be in line with social demand and to take into account genetic diversity as well as required adaption to climate change. Towards these aims, RUMIGEN will ensure engagement of a variety of stakeholders to assess social perception of breeding objectives and related technologies in ruminants. It will define “rooms of acceptance” which will be implemented in sustainable breeding scenarios that will then be assessed through multi-actor panels. To define new breeding programs, RUMIGEN, which brings together partners representing pan-European leaders on ruminant breeding, will question trade-offs and pleiotropic effects through adaptation to environmental stressors such as heat stress. Cosmopolitan and local dairy cattle breeds will be analysed evaluating mid to long term effects as well as impact on next generation (fetal programming). This work will rely on large-scale data from commercial farms combined with climatic data, taking advantage of the large panel of situations across Europe and of a unique design involving half-sister cows raised in contrasted conditions, Denmark and India. Diversity will be also studied with new breed genome assemblies. Methods will be developed to account for rare alleles and to maintain diversity. An epigenotyping platform will be designed to (i) explore sperm epigenome influences on bull fertility and progeny, (ii) decipher underlying mechanisms of epigenetic inheritance and (iii) evaluate how much epigenetic biomarkers improve phenotype prediction. RUMIGEN will answer questions on genome editing specificity and safety issues, assessing its potential to preserve genetic diversity and increase genetic gains. Overall, RUMIGEN will develop models combining genomics, epigenomics and biotechnologies to improve genomic selection, preserve genetic biodiversity and avoid genetic load. Improved phenotype prediction will pave the way to new management indexes for precision farming.
| Aarhus Universitet | 303 370 € |
| Agencia Estatal Consejo Superior de Investigaciones Cientificas | 517 905 € |
| Danmarks Tekniske Universitet | 18 443,00 € |
| Eliance | 485 644 € |
| EUROPEAN FORUM OF FARM ANIMAL BREEDERS | 337 375 € |
| Federazione Europea Di Zootecnica | 125 100 € |
| Fonden Democracy X | 459 075 € |
| Inrae Transfert SAS | 360 004 € |
| Institut de l'Elevage | 445 761 € |
| Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement | 1 150 976 € |
| Instituto Regional de Investigacion y Desarrollo Agroalimentario y Forestal de Castilla-La Mancha | 32 885 € |
| Norges Miljo-og Biovitenskapelige Universitet | 644 460 € |
| STICHTING WAGENINGEN RESEARCH | 442 185 € |
| Sveriges Lantbruksuniversitet | 226 033 € |
| The University of Edinburgh | 575 000 € |
| Universite de Liege | 157 633 € |
| Valogene | 363 063 € |
| WAGENINGEN UNIVERSITY | 353 941 € |
https://cordis.europa.eu/project/id/101000226
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.