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Financement de l’UE (150 000 €) : Dosage par sonde fluorescente commutable en une étape pour la détection directe des virus. Hor 23/04/2021 Programme de recherche et d'innovation de l'UE « Horizon »
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Dosage par sonde fluorescente commutable en une étape pour la détection directe des virus.
Since March 2020, the world is facing the Covid-19 pandemic. As of September 2020, over 900 000 people have died of the disease, caused by the SARS-CoV-2 virus. The WHO recommendations in order to limit the spread of the virus are to “test, trace and isolate”. To be successful, this strategy requires fast and massive testing. Today, tests are performed using PCR, a resource-intensive process requiring extraction of the viral RNA before nucleic acid amplification. PCR tests are slow (several hours) and require an army of advanced laboratory equipment or automated diagnostic workflow setups for the various steps, and thus prevalent in centralized facilities testing samples in large batches. Consequently, the turn-around time for these tests has proven to be 24-48 hours globally. Here, we propose to develop a new Covid-19 test, 1-SWITCH, consisting of a single step switchable fluorescent probe assay. The 1-SWITCH technology will use low cost reagents, and therefore will be cheaper than current available Covid-19 tests. The sensitivity of the test will be superior to the one of antigen tests and comparable to the one of PCR tests. This 1-step, 1-tube method will detect the virus directly within minutes and eliminates the assay complexity, thus facilitating smoother workflows in laboratory diagnostics as well as point of care screening. This will consist of a major breakthrough in clinical diagnostics. Plans for bringing our research finding to a commercial innovation are presented.
| Lunds Universitet | 150 000 € |
https://cordis.europa.eu/project/id/966778
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Lunds Universitet, Lund, Suède.
