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Financement de l’UE (5 999 889 €) : LETHE (λήθη) – Un modèle de prédiction et d’intervention personnalisé pour la détection précoce et la réduction des facteurs de risque causant la démence, basé sur … Hor09/12/2020 Programme de recherche et d'innovation de l'UE « Horizon »
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LETHE (λήθη) – Un modèle de prédiction et d’intervention personnalisé pour la détection précoce et la réduction des facteurs de risque causant la démence, basé sur l’IA et l’apprentissage automatique distribué
As the world's population increases in age, the number of people living with dementia grows. Dementia has long been considered to be neither preventable nor treatable, but while the underlying illnesses are not curable, today we know that the disease course might be modifiable with good preventive interventions at an early time point. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) showed a positive effect after a 2-year intervention targeting several lifestyles and vascular risk factors simultaneously. LETHE will go beyond and provide a data-driven risk factor prediction model for older individuals at risk of cognitive decline building upon big data analysis of cross-sectional observational and longitudinal intervention datasets from 4 clinical centers in Europe including the 11- years analysis of FINGER. LETHE will establish novel digital biomarkers, for early detection of risk factors, based on unobtrusive ICT-based passive and active monitoring. The aim is to establish a digital-enabled intervention for cognitive decline prevention based on the evolution of a successful protocol (FINGER) evolving into an ICT based preventive lifestyle intervention through individualized profiling, personalized recommendations, feedback and support (FINGER 2.0), well targeted on a population stratified by cost-effective biological biomarkers. The LETHE solution will be tested in a feasibility study validating the achieved improvements. A successful LETHE project could lead to a more personalized risk factor prevention for persons with beginning cognitive decline, thereby empowering people to an active and healthy lifestyle. Expansions of prevention trials on large scale by an automatized roll out of a multimodal intervention approach, reaching out to large populations, could save future costs on expensive traditional interventions and confer benefits for the wider society.
| Alzheimer Europe | 222 500 € |
| Combinostics Oy | 387 580 € |
| Extra RED Srl | 305 875 € |
| FH Joanneum GmbH | 642 000 € |
| I2Grow Innovation TO Grow Srl | 288 706 € |
| Idryma Technologias Kai Erevnas | 495 000 € |
| Infotrend Innovations Company Ltd. | 328 750 € |
| Kaasa Solution GmbH | 347 500 € |
| Karolinska Institutet | 481 262 € |
| Medizinische Universitaet Wien | 502 318 € |
| Stichting EGI | 339 500 € |
| Terveyden JA Hyvinvoinnin Laitos | 750 625 € |
| THE Lisbon Council for Economic Competitiveness ASBL | 212 500 € |
| Universita Degli Studi Di Perugia | 408 750 € |
| Universiteit Maastricht | 287 023 € |
https://cordis.europa.eu/project/id/101017405
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.