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Financement britannique (363 284 £) : Connexions synaptiques et propriétés électrophysiologiques des neurones dans le noyau intermédiaire du bulbe rachidien Ukri 01/01/2008 Recherche et innovation du Royaume-Uni, Royaume Uni
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Connexions synaptiques et propriétés électrophysiologiques des neurones dans le noyau intermédiaire du bulbe rachidien
| Abstract | Experiments in our laboratory have brought to our attention a collection of nerve cells (neurones) whose function is unknown. The neurones are located in a discrete region in the brainstem, the part of the brain that controls body systems critical for breathing and cardiovascular maintenance. The nucleus in which the neurones reside is known to receive information from neck muscles when they are stretched, but what this information is used for needs to be determined. Our preliminary evidence supports at least two ideas for cells in this nucleus / signalling neck muscle stretching to circuits involved in cardiorespiratory control and/or those involved in co-ordinating swallowing and breathing. To help determine if the cells participate in controlling such functions, we will investigate what other brain regions they send information to and receive information from using contemporary neuroanatomical methods. This will involve identifying cell types in the other brain regions where possible. We will also closely investigate the anatomical and electrical properties of the cells themselves since these features infleunce how the cells respond to incoming information and therefore how this information is passed on to other neurones. These studies will therefore clarify the connections and functions of an unexplored brain nucleus that we propose is involved in controlling important body functions. |
| Category | Research Grant |
| Reference | BB/F006594/1 |
| Status | Closed |
| Funded period start | 01/01/2008 |
| Funded period end | 31/12/2010 |
| Funded value | £363 284,00 |
| Source | https://gtr.ukri.org/projects?ref=BB%2FF006594%2F1 |
Participating Organisations
| University of Leeds | |
| Japan Science and Technology Agency |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : University of Leeds, LS2 9JT Leeds, Royaume Uni.
