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UK funding (1 720 922 £) : HTS - Maximiser la valeur des banques de cerveaux MRC Ukri01/09/2013 UK Research and Innovation, Royaume Uni
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HTS - Maximiser la valeur des banques de cerveaux MRC
| Abstract | The aim of this study to maximise the value of the brain tissue samples available to the research community in the four MRC-funded brain banks by the systematic analysis and integration of data from genomic studies on cases currently available for research in the banks. . All MRC brain banks have ethics approval to function as tissue banks and to collect, store and release tissue samples and data from consented donors. Consent/authorisation for genetic research is recorded and will be used to identify cases for inclusion in this study. Governance mechanisms include local NHS governance, Human Tissue Authority licences and Healthcare Improvement Scotland accreditation, along with MRC policies on research governance. This study will involve the investigation of normal brains from a wide age range and brains from well-characterised disease cohorts in the MRC brain banks. We aim to genetically characterise 1500 representative brains with Alzheimer disease, dementia with Lewy bodies /Parkinson disease, vascular dementia, frontotemporal dementia/motor neurone disease, Creutzfeldt-Jakob disease and controls. The data generated will greatly enrich the clinical and neuropathological data currently associated with these samples. This work will therefore provide major added value to the exiting brain banks, opening up totally new opportunities for mechanistic and translational research in neurodegeneration and brain aging. |
| Category | Intramural |
| Reference | MC_PC_13044 |
| Status | Closed |
| Funded period start | 01/09/2013 |
| Funded period end | 31/12/2016 |
| Funded value | £1 720 922,00 |
| Source | https://gtr.ukri.org/projects?ref=MC_PC_13044 |
Participating Organisations
| University of Edinburgh | |
| UNIVERSITY COLLEGE LONDON | |
| Cambridge University Hospitals NHS Foundation Trust | |
| UNIVERSITY OF BRISTOL | |
| University of Sheffield | |
| University of Oxford | |
| NEWCASTLE UNIVERSITY | |
| UNIVERSITY OF EDINBURGH | |
| UNIVERSITY OF MANCHESTER | |
| IMPERIAL COLLEGE LONDON | |
| KING'S COLLEGE LONDON |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : University OF Edinburgh CHARITY, Edinburgh, Royaume Uni.
