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UK funding (88 229 £) : Colocalisation et agrégation d’enzymes pour une activité métabolique accrue pour les produits chimiques de base. Ukri01/09/2016 UK Research and Innovation, Royaume Uni
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Colocalisation et agrégation d’enzymes pour une activité métabolique accrue pour les produits chimiques de base.
| Abstract | Current approaches for enhancing bio-based commodity production are restricted to known biosynthetic pathways and limitations to metabolite toxicity. However, many key bio-commodities are made via aldehyde-intermediates such as acetaldehyde, lactaldehyde and propanaldehyde and their production is often limited because of the inherent toxicity of their chemical reactivity. Ways to reduce this toxicity would offer a significant advantage to the commercial production of these materials. This application outlines a major new strategy to reduce the toxicity of key metabolic intermediates such as acetaldehyde through the deployment of proteinaceous scaffolds. This approach will be coupled to a novel pathway that will be engineered in specific bacteria called acetogens that can live on gaseous exhaust fumes in order to produce a key chemical commodity called 1,3-butanediol. |
| Category | Feasibility Studies |
| Reference | 132326 |
| Status | Closed |
| Funded period start | 01/09/2016 |
| Funded period end | 30/11/2017 |
| Funded value | £88 229,00 |
| Source | https://gtr.ukri.org/projects?ref=132326 |
Participating Organisations
| ZUVASYNTHA LIMITED |
£88 229,00 |
| UNIVERSITY OF KENT |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Zuvasyntha Ltd., Knebworth, Royaume Uni.