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Financement de l’UE (3 874 497 €) : Un test de diagnostic pour améliorer la surveillance et la prise en charge des patients atteints de COVID-19 Hor21/10/2020 Programme de recherche et d'innovation de l'UE « Horizon »

Vue d’ensemble

Texte

Un test de diagnostic pour améliorer la surveillance et la prise en charge des patients atteints de COVID-19

Coronavirus disease 2019 (COVID-19) caused by infection with SARS coronavirus 2 (SARS-CoV-2) has reached pandemic proportions with more than 7 million people infected and 0.4 million people killed worldwide. Death rates are accentuated by cardiovascular comorbidities and arrhythmias leading to unexpected major cardiovascular events. Being able to identify COVID-19 patients at risk of developing cardiovascular events leading to death would allow improving surveillance and care. Currently, there is no accurate method to predict outcome of COVID-19 patients. COVIRNA is a patient-centered Innovation Action aiming to satisfy this urgent and unmet need. COVIRNA will complete and deploy a prognostic system based on cardiovascular biomarkers of COVID-19 clinical outcomes combined with digital tools and artificial intelligence analytics (i.e. prediction model). Complementary expertise of 15 EU partners from the healthcare sector, academia, association and industry will allow conducting a large retrospective study on existing cohorts of COVID-19 patients. By upscaling the already validated and patented research use only FIMICS panel of cardiac-enriched long noncoding RNA biomarkers into an in-vitro diagnostic test (COVIRNA) adapted to COVID-19 patients, the project will quickly deliver a minimally-invasive, simple yet robust and affordable prognosis tool that can be used in the context of the current COVID-19 crisis as well as in further major health issues. By tackling the cardiovascular complications in COVID-19, known to contribute significantly to mortality, the project outputs are expected to have a major impact on the pandemic outcomes. The COVIRNA test will be CE-marked and prepared for commercialization, allowing to risk stratify patients, adapt therapies and to inform drug design.


European Health Management Association 151 625 €
Firalis 1 109 588 €
Firalis Molecular Precision SA 0,00 €
HEINRICH-HEINE-UNIVERSITAET DUESSELDORF 50 000 €
Imperial College of Science Technology and Medicine 400 000 €
Institut de Recerca de L'Hospital de La Santa Creu i Sant Pau Fundacion 273 943 €
Institut Jozef Stefan 50 000 €
Internacionalni Univerzitet U Sarajevu 50 000 €
Luxembourg Institute OF Health 699 822 €
PHARMAHUNGARY 2000 KISERLETES ES KLINIKAI KUTATASFEJLESZTESI KORLATOLTFELELOSSEGU TARSASAG 35 000 €
Policlinico SAN Donato S.p.A. 174 388 €
The University of Edinburgh 299 950 €
Universidade de Coimbra 26 058 €
UNIVERSITAET LEIPZIG 199 896 €
Universite Du Luxembourg 199 604 €
UNIVERSITEIT MAASTRICHT 154 625 €

https://cordis.europa.eu/project/id/101016072

Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.