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Financement britannique (80 647 £) : La résistance aux antimicrobiens dans la production porcine et avicole brésilienne et sa contribution au succès des sérotypes de Salmonella Ukri 01/05/2018 Recherche et innovation du Royaume-Uni, Royaume Uni
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La résistance aux antimicrobiens dans la production porcine et avicole brésilienne et sa contribution au succès des sérotypes de Salmonella
| Abstract | Antimicrobial resistance (AMR) of bacteria found in livestock represent a grave threat to the health of both animals and humans; resistant infections in livestock also have a significant economic impact. Salmonella enterica is one of the most important bacterial pathogens in pigs and poultry, which are thought to be two of the major reservoirs for human infections. Brazil is one of the world's largest producers and exporters of pig and chicken meat, and these industries are significant contributors to the country's economy. Change in these production systems over the last 10 years, including massive intensification and introduction of a Salmonella Enteritidis vaccine in poultry, have led to dramatic shifts in the Salmonella serotype prevalence observed from pigs and poultry in Brazil. These shifts are probably driven by antimicrobial use and resistance, but this issue has not been fully investigated. The research outlined in our proposal will investigate the diversity and evolution of AMR determinants in Salmonella isolated from Brazilian pigs and poultry over the last 10 years. We will use whole genome sequencing, and state-of-the-art long read sequencing, combined with molecular biology and epidemiology to explore the role of AMR in the success of different Salmonella serotypes in these populations. This proposal represents a new collaboration between Dr Mather at Quadram Institute Bioscience (QIB) in the UK, and Dr Moreno at the University of São Paulo (USP), along with collaborators Dr Terezinha Knöbl and Dr Luisa Moreno at USP. This research will tackle the huge health and economic threat posed by AMR to Brazilian livestock species, which will help identify where suitable control strategies could be applied most effectively. |
| Category | Research Grant |
| Reference | BB/R022682/1 |
| Status | Closed |
| Funded period start | 01/05/2018 |
| Funded period end | 30/04/2019 |
| Funded value | £80 647,00 |
| Source | https://gtr.ukri.org/projects?ref=BB%2FR022682%2F1 |
Participating Organisations
| QUADRAM INSTITUTE BIOSCIENCE | |
| Universidade de São Paulo |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Quadram Institute Bioscience, Norwich, Royaume Uni.