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Financement britannique (1 026 681 £) : Nouvelle technologie d’édition génomique CRISPR Guided Vector pour remplacer l’utilisation d’antibiotiques dans la production d’animaux d’élevage Ukri 01/09/2018 Recherche et innovation du Royaume-Uni, Royaume Uni
Vue d’ensemble
Texte
Nouvelle technologie d’édition génomique CRISPR Guided Vector pour remplacer l’utilisation d’antibiotiques dans la production d’animaux d’élevage
| Abstract | "Antibiotic overuse contributes to increasing the reservoir of resistant bacteria, resulting in increased human mortality (10million deaths a year globally by 2050), increased hospital stay lengths (20-30days), and estimates of global direct- and indirect- costs up to c.£77 trillion. Currently, no new antibiotics are under development and alternatives are ineffective. Consequently, animal production globally is under increasing pressure to reduce antibiotic use as resistance here enters the human food chain. However, limiting the availability of medical interventions to prevent and control animal disease on the farm is directly impacting global food security and food safety. Therefore, there is a major unmet need for effective alternative treatments to antibiotics which are simple, cheap and more sustainable compared to current methods. This project seeks to develop the use of a novel gene editing technology to target a range of currently prevalent bacterial pathogens and deliver a 100% killing system. This will enable Folium, in collaboration with the University of Bristol and the Quadram Institute of Bioscience to establish a leading market position as the first company to formulate this specific genetic technology in to a product range for livestock treatment. The impact of this project would provide an initial cost avoidance to the livestock industry of c.£128million by offering an alternative to current treatment methods and reducing antibiotic resistance in the food supply chain, with potential to go on and transfer this technology to crop treatment applications, human health applications and manufacturing cleaning solutions." |
| Category | Collaborative R&D |
| Reference | 104289 |
| Status | Closed |
| Funded period start | 01/09/2018 |
| Funded period end | 29/02/2020 |
| Funded value | £1 026 681,00 |
| Source | https://gtr.ukri.org/projects?ref=104289 |
Participating Organisations
| FOLIUM FOOD SCIENCE LIMITED |
£697 289,00 |
| QUADRAM INSTITUTE BIOSCIENCE |
£153 918,00 |
| UNIVERSITY OF BRISTOL |
£175 474,00 |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Folium Food Science Ltd., Leeds, Royaume Uni.
