Moteur de recherche d’entreprises européennes
Financement britannique (871 781 £) : L’eau comme milieu réactionnel synthétique : concrétiser sa qualification en chimie verte Ukri 01/06/2019 Recherche et innovation du Royaume-Uni, Royaume Uni
Vue d’ensemble
Texte
L’eau comme milieu réactionnel synthétique : concrétiser sa qualification en chimie verte
| Abstract | This project aims to deliver the underpinning tools and design principles to support the use of water as a reaction media in High Value Chemical Manufacture. Water has long been promoted as an environmentally friendly and safe 'green' reaction media for synthetic processes which can lead to much more sustainable and cost effective manufacturing process. Nevertheless, the green credential of water has been limited due to issues related to organic contamination of the water waste stream, cost of subsequent treatment and the often required organic solvents at purification stage. Water-accelerated reactions, i.e. reactions which proceed faster in water than in organic solvents and wherein organic reactants and products form hydrophobic droplets, are potential game-changers High Value Chemical Manufacture. They benefit from accelerated rates, improved productivity and much improved green metrics through reduction in the use of organic solvents. Their current limitations are: (i) a limited pool of known reactions; (ii) lack of suitable equipment and process understanding; and (iii) insufficient understanding of acceleration effects which can guide discovery and process design. This project will address these knowledge gaps and deliver the following critical outputs, identified through discussion with our industrial partners in chemical industry sector: (i) a wider range of synthetically useful water-accelerated reactions, (ii) multi-scale batch and flow reactors to support the scale-up pathway for water-accelerated processes, (iii) standardised protocols for characterising such processes and basic process understanding for scaling up, and (iv) streamlined workup/product purification and recycling of water to truly deliver green processes. These outputs will have transformative impacts in the chemical manufacture industry, delivering lower cost and better quality controlled processes through shorter routes, reduced organic waste and facile interfacing between chemo- and biocatalytic processes. |
| Category | Research Grant |
| Reference | EP/S013768/1 |
| Status | Closed |
| Funded period start | 01/06/2019 |
| Funded period end | 30/06/2023 |
| Funded value | £871 781,00 |
| Source | https://gtr.ukri.org/projects?ref=EP%2FS013768%2F1 |
Participating Organisations
| University of Leeds | |
| Astrazeneca | |
| Newcastle University | |
| AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) | |
| Asynt | |
| AstraZeneca | |
| Concept Life Sciences | |
| IMPERIAL COLLEGE LONDON | |
| Sterling Pharma Solutions Ltd. | |
| Dr Reddy's Laboratories UK Ltd |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : University of Leeds, LS2 9JT Leeds, Royaume Uni.
