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Financement de l’UE (4 999 568 €) : Centre d’excellence HPC/Exascale en médecine personnalisée - PerMedCoE Hor14/08/2020 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Centre d’excellence HPC/Exascale en médecine personnalisée - PerMedCoE
Personalised Medicine (PerMed) opens unexplored frontiers to treat diseases at the individual level combining clinical and omics information. However, the performances of the current simulation software are still insufficient to tackle medical problems such as tumour evolution or patient-specific treatments. The challenge is to develop a sustainable roadmap to scale-up the essential software for the cell-level simulation to the new European HPC/Exascale systems. Simulation of cellular mechanistic models are essential for the translation of omic data to medical relevant actions and these should be accessible to the end-users in the appropriate environment of the PerMed-specific big confidential data. The goal of the HPC/Exascale Centre of Excellence in Personalised Medicine (PerMedCoE) is to provide an efficient and sustainable entry point to the HPC/Exascale-upgraded methodology to translate omics analyses into actionable models of cellular functions of medical relevance. It will accomplish so by 1) optimising four core applications for cell-level simulations to the new pre-exascale platforms; 2) integrating PerMed into the new European HPC/Exascale ecosystem, by offering access to HPC/Exascale-adapted and optimised software; 3) running a comprehensive set of PerMed use cases; & 4) building the basis for the sustainability of the PerMedCoE by coordinating PerMed and HPC communities, and reaching out to industrial and academic end-users, with use cases, training, expertise, and best practices. The PerMedCoE cell-level simulations will fill the gap between the molecular- and organ-level simulations from the CompBioMed and BioExcel CoEs with which this proposal is aligned at different levels. It will connect methods’ developers with HPC, HTC and HPDA experts (at POP and HiDALGO CoEs). Finally, the PerMedCoE will work with biomedical consortia (i.e. ELIXIR, LifeTime initiative) and pre-exascale infrastructures (BSC and CSC), including a substantial co-design effort.
| Atos IT Solutions And Services Iberia SL | 0,00 € |
| Atos Spain SA | 420 404 € |
| Barcelona Supercomputing Center Centro Nacional de Supercomputacion | 1 188 774 € |
| CSC-Tieteen Tietotekniikan Keskus Oy | 509 900 € |
| Elem Biotech SL | 104 375 € |
| European Molecular Biology Laboratory | 378 974 € |
| Fundacio Centre de Regulacio Genomica | 122 500 € |
| Fundacio Institut de Recerca Biomedica (Irb Barcelona) | 0,00 € |
| Institut Curie | 508 750 € |
| Kungliga Tekniska Hoegskolan | 299 875 € |
| Max Delbrueck Centrum Fuer Molekulare Medizin IN DER Helmholtz-Gemeinschaft (MDC) | 149 425 € |
| Universitatsklinikum Heidelberg | 473 500 € |
| Universite Du Luxembourg | 739 840 € |
| Univerza V Ljubljani | 103 250 € |
https://cordis.europa.eu/project/id/951773
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.
