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Financement de l’UE (3 923 653 €) : Immunologie quantitative des lymphocytes T et immunothérapie Hor 28/06/2018 Programme de recherche et d'innovation de l'UE « Horizon »

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Texte

Immunologie quantitative des lymphocytes T et immunothérapie

Health and disease are regulated, to a large extent, by our immune system. The immune system not only protects the body from infectious disease, but is involved in a number of conditions of increasing incidence and morbidity, such as diabetes, rheumatoid arthritis, inflammatory bowel disease and allergies. In cancer, the immune system can be both cause and cure; it contributes to chronic inflammation that promotes tumour development, but it can also provide the ultimate weapon against metastatic disease. Thus, the development of ways to harness, direct or restrain immune responses has great potential for enhancing human health. Understanding the mechanisms that control the abundance of different lymphocyte (a type of white blood cell) subsets is key to therapeutically targeting immune responses. Ultimately, this understanding must be sought in quantitative terms, explaining how the rates of cell proliferation, differentiation, survival and death are determined by molecular mechanisms and cellular interactions. Current immunological research is beginning to combine experimental approaches with mathematical analysis to quantitate immune dynamics. A severe obstacle to more rapid progress in this area is the lack of appropriately trained scientists. In this ETN, European scientists, with a rich track record in collaborative research and training, have come together to deliver a highly collaborative, multidisciplinary and intersectoral research training programme for 15 early stage researchers (ESRs) in Quantitative T cell Immunology and Immunotherapy (QuanTII).


Astrazeneca UK Ltd. 273 288 €
Bayer AG 498 433 €
Centre National de la Recherche Scientifique CNRS 262 876 €
Deutsches Krebsforschungszentrum Heidelberg 498 433 €
Imperial College of Science Technology and Medicine 273 288 €
Medimmune Ltd. 0,00 €
National University of Ireland Maynooth 265 675 €
Universitair Medisch Centrum Utrecht 510 749 €
Universiteit Utrecht 255 374 €
University of Galway 265 675 €
University of Leeds 819 864 €

https://cordis.europa.eu/project/id/764698

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