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Financement de l’UE (3 997 825 €) : iFERMENTER - CONVERSION DES FLUX RÉSIDUELS DE SUCRE FORESTIER EN PROTÉINES ANTIMICROBIENNES PAR FERMENTATION INTELLIGENTE Hor 01/05/2018 Programme de recherche et d'innovation de l'UE « Horizon »
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iFERMENTER - CONVERSION DES FLUX RÉSIDUELS DE SUCRE FORESTIER EN PROTÉINES ANTIMICROBIENNES PAR FERMENTATION INTELLIGENTE
Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and contribute to a sustainable bioeconomy. Unfortunately, existing biorefineries struggle with technical issues and low profitability due to the lack of adequate fermentation processes. Therefore, these sugars are either incinerated to generate energy or at best converted to ethanol (€0.6 /kg) but not to higher value chemicals. Current concepts that aim to establish fermentation processes to convert residual sugar streams to high value products face challenges including inefficient sugar utilization by microorganisms and inhibitors in the residual streams, leading to low productivity and yields. Our project aims to recover high value compounds from sugar residuals, and to turn fermentation processes converting these residual to antimicrobials cost effective. We will recover the high value sugar galactose (€40-200 /kg) from residual streams as part of their treatment process. By genome editing technique, we will design cell factories that consume the remaining residuals and produce nisin (€50-150 /kg), an industrially important commercial food/feed preservative. Additionally, we will develop an affordable, online feedback add-on system that will allow to intelligently change residual mixture during fermentation of these cell factories to optimize production online during the process. In a 150 L industrial bioreactor, we will demonstrate that our add-on invention iFermenter - increases the yields of nisin by over 2 fold - increases the pediocin production by over 50% compared to what is possible today, - and reduce at least 20% in CO2 footprint with this process compared to existing solutions. Thus, iFermenter will render production of high value products with residual sugar stream highly efficient and cost-effective contributing to circular economy.
| Bio Base Europe Pilot Plant VZW | 438 474 € |
| Borregaard AS | 0,00 € |
| Danmarks Tekniske Universitet | 250 395 € |
| Galactic SA | 0,00 € |
| Infors AG | 79 875 € |
| Mybiotech GmbH | 128 025 € |
| Norges Miljo-og Biovitenskapelige Universitet | 146 500 € |
| Norges Teknisk-Naturvitenskapelige Universitet Ntnu | 995 025 € |
| Technische Universitaet Wien | 728 266 € |
| Universidad de Santiago de Compostela | 179 390 € |
| Universitaet ULM | 438 000 € |
| Universitat DES Saarlandes | 613 875 € |
https://cordis.europa.eu/project/id/790507
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel.