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Financement de l’UE (160 800 €) : Activité anticancéreuse d’un milieu activé par le plasma et ses mécanismes sous-jacents : étude expérimentale et computationnelle combinée Hor21/02/2017 Programme de recherche et d'innovation de l'UE « Horizon »
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Activité anticancéreuse d’un milieu activé par le plasma et ses mécanismes sous-jacents : étude expérimentale et computationnelle combinée
Cold atmospheric plasma (CAP) is gaining increasing interest for cancer treatment, although the application is still in its early stages. Besides direct CAP treatment of cancer cells, plasma can also be used to activate a liquid medium, which seems to have similar anti-cancer effects as the plasma itself. This so-called plasma activated medium (PAM) is very promising for cancer treatment, as it can be more generally used, e.g., it might be directly injected into tissue of patients. However, the anticancer potential of PAM is not yet fully understood. This is exactly the focus of this project. We will measure the reactive oxygen and nitrogen species (RONS) concentrations in PAM, and also calculate them with a model for plasma-liquid interaction. In addition, we will study the effect of PAM on a catalase model protein by experiments, and perform atomic scale simulations for the interaction of RONS with this protein, to better understand the effect of PAM on cancer cells, because catalase aids cancer cells in overcoming oxidative stress created by PAM.
| Universiteit Antwerpen | 160 800 € |
https://cordis.europa.eu/project/id/743546
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Universiteit Antwerpen, Anvers, Belgique.