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Financement de l’UE (731 400 €) : Étude théorique et computationnelle du développement de la résistance antimicrobienne de la tuberculose sur la base d’une vaste bibliothèque expérimentale de souches … Hor 13/11/2018 Programme de recherche et d'innovation de l'UE « Horizon »
Texte
Étude théorique et computationnelle du développement de la résistance antimicrobienne de la tuberculose sur la base d’une vaste bibliothèque expérimentale de souches de mycobactéries
Multidrug resistance of Mycobacterium tuberculosis is declared a serious global threat by the World Health Organization. Our project aims at developing a comprehensive model of molecular mechanisms responsible for antimicrobial drug resistance of tuberculosis. Isoniazid is the main drug used for TB treatment, because it interacts with the bacterial catalase that leads to the bacterial death. The library of isoniazid resistant strains (over 100 different strains) will be used as experimental basis for building theoretical and computational models of the molecular processes leading to drug resistance of mutated bacteria. The model will be used for suggesting effective treatment targeting these mechanisms and overcoming the resistance. AMR-TB RISE will be used to utilise the expertise of highly specialised research groups of biologists, clinicians, biochemists, physicists, computer engineers, and mathematicians allowing the researches from these groups to work in multiple laboratories of the Consortium all over the world. Particular attention will be given to training the next generation of young researcher and forming tightly interconnected, long term collaboration devoted to solving the pressing global problem of antimicrobial resistance not only in TB, but in a wide spectrum of diseases.
| Escuela Politecnica Nacional | ? |
| Agencia Estatal Consejo Superior de Investigaciones Cientificas | 9 200,00 € |
| Aston University | 202 400 € |
| Freie Universitaet Berlin | 9 200,00 € |
| GPU Prime Ltd. | 27 600 € |
| Institut Biohimii IM.O.V. Palladina Nacionalnoy Akademii Nauk Ukraini | 207 000 € |
| Taras Shevchenko National University OF Kyiv | 115 000 € |
| Universidad Rey Juan Carlos | 41 400 € |
| Universita Degli Studi Di Messina | 46 000 € |
| University of Leicester | 4 600,00 € |
| University of Surrey | 13 800,00 € |
| University of Warwick | 18 400,00 € |
| V. N. Karazin Kharkiv National University | 36 800 € |
https://cordis.europa.eu/project/id/823922
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : EPN Ecuador, Quito, Équateur.
