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Financement de l’UE (149 633 €) : Profilage métabolique du microbiome vaginal pour la santé reproductive Hor18/03/2019 Programme de recherche et d'innovation de l'UE « Horizon »
Vue d’ensemble
Texte
Profilage métabolique du microbiome vaginal pour la santé reproductive
There is ever increasing evidence that the vaginal microbiome plays an important role in reproductive health. Studies have shown that dysbiotic states can culminate in bacterial vaginosis, urinary tract infections and premature birth. Although the microbiome is usually characterised by 16S rRNA sequencing, the methodology is time consuming and expensive. Here we describe the development of a desorption ionisation mass spectrometry (DESI-MS) based technique which characterises microbial community structures based upon metabolomic analysis. The technique has been successfully demonstrated for a range of applications and here we describe its commercial development as a diagnostic tool, firstly, for assessing the potential success rates of in vitro fertilisation treatments and, secondly, for stratifying patients at higher risk of pre-term birth. During the first 12 months of the project the technology will be assessed using a unique sample set collected as part of two longitudinal cohort studies. During the later stages a thorough market assessment will be performed to identify the addressable demand and to evaluate market competitors. It is envisioned that this information will allow an in depth business case, including our current intellectual property position, to be written, from which further funding can be obtained for the eventual creation of a spin out company.
| Imperial College of Science Technology and Medicine | 149 633 € |
https://cordis.europa.eu/project/id/825813
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : Imperial College of Science Technology and Medicine, Londres, Royaume Uni.
