Moteur de recherche d’entreprises européennes
UK funding (82 029 £) : Régulation de la stabilité des protéines par hydroxylation de la lysine Ukri05/01/2023 UK Research and Innovation, Royaume Uni
Vue d’ensemble
Texte
Régulation de la stabilité des protéines par hydroxylation de la lysine
| Abstract | Cells control the rates and extent to which 'worker' proteins are produced and eliminated as a means to control physiological processes, including development and ageing. To distinguish proteins to be retained from those to be disposed of, cells use a code of alterations to proteins known as post-translational modifications (PTMs). When something goes wrong in such a complex and intricate set of processes it can lead to disease. While a number of PTMs have been characterized, many others remain to be discovered and their biological functions remain elusive. In the Fellowship, I will use a combination of biochemical, biophysical and cellular studies to shine light on an unprecedented and recently-identified PTM involving atmospheric oxygen. The results will help us to understand how cells determine protein lifetimes as a function of their environment. |
| Category | Fellowship |
| Reference | BB/T009454/2 |
| Status | Closed |
| Funded period start | 05/01/2023 |
| Funded period end | 31/12/2023 |
| Funded value | £82 029,00 |
| Source | https://gtr.ukri.org/projects?ref=BB%2FT009454%2F2 |
Participating Organisations
| University of Dundee |
Cette annonce se réfère à une date antérieure et ne reflète pas nécessairement l’état actuel. L’état actuel est présenté à la page suivante : University of Dundee, Dundee, Royaume Uni.
